Description:Coronary artery disease (CAD) causes severe disability and more death than any other disease in affluent societies, including cancer. The medical conditions associated with it are angina, ischaemia, unstable angina, myocardial infarction, arrhythmias, heart failure and sudden death. Choosing the appropriate investigation to confirm a diagnosis helps to assess risk and determine the correct treatment path. GPs also need to know the effective life-style and risk-factor modifications in addition to advocating the best medical therapy. Coronary artery disease is almost always due to atheromatous narrowing and subsequent occlusion of the vessel. Early atheroma (from the Greek athera (porridge) and oma (lump)) is present from young adulthood onwards. A mature plaque is composed of two constituents, each associated with a particular cell population. The lipid core is mainly released from necrotic “foam cells”—monocyte derived macrophages, which migrate into the intima and ingest lipids.
No hay comentarios:
Publicar un comentario